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They found the gene editing methods produced similar results. To determine the effectiveness of CRISPR for gene editing, the scientists engineered the Cas9 gene with two different versions of Cas9, a form that is not required for any specific target genome but can be a valuable target for gene editing and is better than the original form for short-range DNA. Under the new design, which will open on July 1st, one-bedroom flats will feature on two levels and will be separated from the three-bedroom homes on the upper levels.

The building will be four storeys high and will feature an "art-like" layout to allow views of Belfast harbour and Belfast river. A second scheme, planned for north Belfast to make way for the new nursing home, is set to open next year. The age of steam brought Cobh association with several milestones, including the first steam ship to sail from Ireland to England and the first steam ship to cross the Atlantic Sirius , which sailed from Passage West.

In , the name of the town was changed to Queenstown, to honour Queen Victoria who had visited Ireland during that year. The survivors and the dead alike were brought to Queenstown, and the bodies of over who perished in the disaster lie buried in the Old Church Cemetery just north of the town. During the First World War , Queenstown was a naval base for British and American destroyers operating against the U-boats that preyed upon Allied merchant shipping.

Q-ships heavily armed merchant ships with concealed weaponry, designed to lure submarines into making surface attacks were called Q-ships precisely because many were, in fact, fitted-out in Queenstown. The first division of American destroyers arrived in May , and the sailors who served on those vessels were the first American servicemen to see combat duty in the war. When that first convoy arrived in port after enduring a rough passage in what were little more than open boats, its members were met by a crowd of sailors and townspeople, thankful for their anticipated help towards stopping the U-boats that were blockading western Europe.

Admiral Sir Lewis Bayly , commander of the Coast of Ireland station, met the senior American officer, Commander Joseph Taussig , at the dock and inquired as to how soon the weatherbeaten American ships could be put to use. The United States Navy established U. Naval Air Station Queenstown in February It operated flying boats during the last months of WW1, and closed in April Due to its tactical military importance, under the terms of the Anglo-Irish Treaty , the port remained a UK sovereign base within the Irish Free State after Along with the other Treaty Ports , it was handed over to the government of the Irish Free State in Tourism is a large employer in Cobh.

Large cruise liners visit Cobh each year, mainly during the summer months, although many of the tourists are transported out of Cobh by bus to other tourist destinations. In all, almost , cruise liner passengers and crew arrive in the town each year when their ships berth right in the centre of the town at the Republic of Ireland's only dedicated cruise terminal.

The town has remained largely unchanged since RMS Titanic departed from Cork Harbour in , with the streetscape and piers still much the same. Facing the town are Spike Island and Haulbowline Island. The latter is the headquarters of the Irish Naval Service , formerly a British naval base. Cobh was home to Ireland's only steelworks, the former state-owned Irish Steel works which was closed by its buyer, Ispat International , in There is a controversy over the slag heap on the steelworks, where there are concerns that it may be leaching into the harbour.

It opened in but ceased operations in the mids. The drydock pumps date from In the 21st century, a number of new developments were completed, such as a new retail park at Ticknock in , and a leisure centre with 25m swimming pool in August In , tours of Spike Island commenced, with tours leaving from Kennedy Pier, near the town centre. Outside of the Dublin metropolitan area, Cobh is one of the few towns in Ireland served by a commuter train service. The town is one of two termini for Cork Commuter Services.

The other is Midleton. Regular commuter services run between Cork city and Cobh , calling at, among others, Fota railway station , Carrigaloe railway station , and Rushbrooke railway station , along the way. Trains run every day and the journey time to Cork is under 25 minutes. Cobh railway station opened on 10 March and was closed for goods traffic on 3 November The nearest airport is Cork Airport , which can be reached in 20—30 minutes from Cobh via the R road and the N25 road. The port's harbour pilot launches are based at the Camber - a pier and dock are at the eastern end of the town. Currently there is only a single road and road bridge that leads onto the Great Island.

This road bridge, Belvelly Bridge , was built in at one of the narrowest points in the channels around Great Island. In a Cross River Ferry was established which allowed cars and passengers to travel from Glenbrook near Monkstown to Carrigaloe on the Great Island.

Passage west

The crossing from Glenbrook to Carrigaloe takes four minutes and runs daily. Reservations are not required. While local administration was overseen by Cobh Town Council for some years, this local government body was abolished in The Sirius Arts Centre is a hub for the arts in Cobh and is located on the waterfront. It hosts cultural events and music concerts both in-house and around Cobh.

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The Cobh Peoples Regatta is held every year around August, [21] and includes on-stage performances from local musicians and performers as well as a pageant to decide the 'Regatta Queen'. The festival typically ends with a fireworks display over the harbour. Cobh was the setting for the Connor McPherson film The Eclipse , [23] and also used as a filming location for the movie Angela's Ashes. Cobh has several primary and secondary schools including Colaiste Muire secondary school and Cobh Community College. Scoil Iosaef Naofa is a boys primary school in the town, and has reached the Sciath na Scoil finals in hurling and gaelic football on several occasions.